All STI CTG Protocols

STI CTG Protocols

Since its inception in 2005, the STI CTG has received a total of 89 Concepts. Each Concept was reviewed by the Executive Committee for responsiveness to the STI CTG mission. Concepts consistent with the STI CTG mission were then assessed by the Scientific Review Committee.

5 protocols are pending submission to the STI CTG

8 protocols are under development (1 protocol in collaboration)
1 study is actively enrolling participants
2 studies have reached their enrollment goals

2 studies are in data analysis
Currently, the network is facilitating 18 studies in various stages
 

Status	Title
Pending Submission	Safety and Immunogenicity of Heplisav™ in HIV-infected Persons
Pending Submission	GenProbe APTIMA Trichomonas Test - Progression to 510(k)
Pending Submission	A non-inferiority trial of oral therapy (cefpodoxime 400mg & azithromycin 1gm) compared with intramuscular therapeutic injection (ceftriaxone 125mg) for treatment of pharyngeal gonorrhea
Pending Submission	Phase 0 Demonstration project of an STI e-Health System for STI Diagnosis and Treatment
Pending Submission	A RCT of Single vs. Multiple (3 Weekly) Dose Benzathine Penicillin G for Early Syphilis Therapy of Persons With and Without HIV.
In Development	Randomized Trial of Patient Delivered Partner Therapy vs. Standard Partner Referral for Prevention of Persistent or Recurrent Chlamydial Infection and Adverse Outcomes in Pregnant Women
In Development	Self-Obtained Vaginal Swabs for the Detection of Chlamydia trachomatis and Neisseria gonorrhoeae
In Development	Preventing Vaginal Infections in Women at Risk for HIV-1
In Development	Syphilis Chemoprophylaxis in Homosexual Men with HIV infection Using Doxycycline
In Development	Randomized Clinical Trial Evaluating Efficacy of Gentamicin/Azithromycin and Gemifloxacin/Azithromycin and Combination Therapies as a Salvage Regimen for Uncomplicated Urogenital Gonorrhea
In Development	Phase 1 Study of the Safety and Tolerability of 3% w/w SPL7013 Gel (VivaGel™) Following Rectal Administration Once Daily for Seven Days in Healthy Male and Female Volunteers
Enrolling	Randomized Clinical Trial Evaluating Treatment Failure Following Recommended Therapy (Azithromycin versus Doxycycline) for Genital Chlamydial Infection in Females in Youth Correctional Facilities
Enrolling	Home Screening for Bacterial Vaginosis to Prevent STDs
Closed to Enrollment	Phase II Randomized, Placebo-Controlled Double-Blind 4-arm Trial for the Treatment of Non-Gonococcal urethritis (NGU): Doxycycline (Plus or Minus Tinidazole) Verses Azithromycin (Plus or Minus Tinidazole)
Closed to Enrollment	A Phase III Equivalence Trial of Azithromycin vs. Benzathine Penicillin for the Treatment of Early Syphilis
Closed	Assessing recruitment and enrollment strategies for STI studies
Closed	An Expanded Phase I Randomized Placebo Controlled Trial of the Safety and Tolerability of 3% w/w SPL7013 Gel (VivaGel™) in Healthy Young Women When Administered Twice Daily for 14 Days